Michaelis-Menten kinetics, the operator-repressor system, and least squares approaches

The Michaelis-Menten (MM) function is a fractional linear function depending on two positive parameters.These can be estimated by nonlinear or linear least squares methods.The non-linear methods, based directly on the defect of the MM function, can fail and not produce any minimizer.The linear met...

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Bibliographic Details
Main Author: Karl Peter Hadeler
Format: Article
Language:English
Published: AIMS Press 2013-07-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2013.10.1541
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