Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature

We report the first known case of a retroperitoneal leiomyosarcoma that presented with an endoscopically defined source of gastrointestinal bleeding in the colon. A 68-year-old male with a history of diverticulosis, hypertension, and hypercholesterolemia who complained of a 3-month history of abdomi...

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Main Authors: Dominic G. Ventura, Shyam J. Thakkar, Katie Farah
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2011/358680
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author Dominic G. Ventura
Shyam J. Thakkar
Katie Farah
author_facet Dominic G. Ventura
Shyam J. Thakkar
Katie Farah
author_sort Dominic G. Ventura
collection DOAJ
description We report the first known case of a retroperitoneal leiomyosarcoma that presented with an endoscopically defined source of gastrointestinal bleeding in the colon. A 68-year-old male with a history of diverticulosis, hypertension, and hypercholesterolemia who complained of a 3-month history of abdominal pain, nausea, and intermittent hematochezia presented for evaluation of large volume hematochezia and lightheadedness. Colonoscopy revealed left-sided diverticulosis and rectal varices without stigmata of recent bleed. CT scan showed a 26 × 20 × 13 cm heterogeneous retroperitoneal mass and multiple hypodense hepatic lesions. Liver biopsy revealed leiomyosarcoma. In summary, although surgery is the mainstay of treatment, resectability has not improved significantly. Early recognition and aggressive surgery are keys to long-term survival.
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issn 2090-6528
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publishDate 2011-01-01
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-63a0719f57b64a8d825beb93be85597c2025-02-03T01:12:58ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362011-01-01201110.1155/2011/358680358680Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the LiteratureDominic G. Ventura0Shyam J. Thakkar1Katie Farah2Allegheny Center for Digestive Health, West Penn Allegheny Health System, Pittsburgh, PA 15212, USAAllegheny Center for Digestive Health, West Penn Allegheny Health System, Pittsburgh, PA 15212, USAAllegheny Center for Digestive Health, West Penn Allegheny Health System, Pittsburgh, PA 15212, USAWe report the first known case of a retroperitoneal leiomyosarcoma that presented with an endoscopically defined source of gastrointestinal bleeding in the colon. A 68-year-old male with a history of diverticulosis, hypertension, and hypercholesterolemia who complained of a 3-month history of abdominal pain, nausea, and intermittent hematochezia presented for evaluation of large volume hematochezia and lightheadedness. Colonoscopy revealed left-sided diverticulosis and rectal varices without stigmata of recent bleed. CT scan showed a 26 × 20 × 13 cm heterogeneous retroperitoneal mass and multiple hypodense hepatic lesions. Liver biopsy revealed leiomyosarcoma. In summary, although surgery is the mainstay of treatment, resectability has not improved significantly. Early recognition and aggressive surgery are keys to long-term survival.http://dx.doi.org/10.1155/2011/358680
spellingShingle Dominic G. Ventura
Shyam J. Thakkar
Katie Farah
Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
Case Reports in Gastrointestinal Medicine
title Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
title_full Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
title_fullStr Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
title_full_unstemmed Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
title_short Retroperitoneal Leiomyosarcoma Presenting as Lower Gastrointestinal Bleeding: A Case Report and Review of the Literature
title_sort retroperitoneal leiomyosarcoma presenting as lower gastrointestinal bleeding a case report and review of the literature
url http://dx.doi.org/10.1155/2011/358680
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AT katiefarah retroperitonealleiomyosarcomapresentingaslowergastrointestinalbleedingacasereportandreviewoftheliterature