Clinical spectrum and uncommon features of McCune-Albright syndrome in children: a cohort study from a National Referral Center

IntroductionMcCune-Albright syndrome (MAS) is a rare disease caused by somatic gain-of-function variants in the GNAS gene that lead to constitutive activation of the G protein alpha subunit (Gsα). Pathologic consequences can involve several tissues. Fibrous dysplasia (FD), café-au-lait skin macules...

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Bibliographic Details
Main Authors: Solène Bergignat, Roland Chapurlat, Marc Nicolino, Kevin Perge
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1531765/full
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