Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation
There are numerous biomonitoring programs, both recent and ongoing, to evaluate environmental exposure of humans to chemicals. Due to the lack of exposure and kinetic data, the correlation of biomarker levels with exposure concentrations leads to difficulty in utilizing biomonitoring data for biolog...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Journal of Toxicology |
Online Access: | http://dx.doi.org/10.1155/2012/760281 |
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