Propofol Causes Consciousness Loss by Affecting GABA-A Receptor in the Nucleus Basalis of Rats

Objective. Propofol is a classical anesthetic and induces consciousness loss, and gamma-aminobutyric-acid-type-A (GABA-A) receptor is its target. Righting reflex is associated with conscious response. The nucleus basalis (NB) acts as a major relay between the reticular activating system and the fron...

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Bibliographic Details
Main Authors: Yunlong Xing, Kai Li, Yuan Jiao, Zinan Li
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2020/9370891
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