Amelioration of metabolic disorders by a mushroom-derived polyphenols correlates with the reduction of Ruminococcaceae in gut of DIO mice

Amelioration of metabolic disorders by a mushroom-derived polyphenols correlates with the reduction of Ruminococcaceae in gut of DIO mice

A polyphenolic alkaloid-enriched extract (PAE) was prepared from the fruiting bodies of a wild edible mushroom Sarcodon leucopus. Oral administration of PAE reduced hyperglycemia, hyperlipidemia, hepatic steatosis, and LPS-related inflammation in high fat diet-induced obese (DIO) mice. Furthermore,...

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Bibliographic Details
Main Authors: Li Sun, Li Bao, Dorji Phurbu, Shanshan Qiao, Shanshan Sun, Yangzom Perma, Hongwei Liu
Format: Article
Language:English
Published: Tsinghua University Press 2021-07-01
Series:Food Science and Human Wellness
Subjects:
Sarcodon leucopus
Polyphenolic alkaloids
Metabolic syndrome
Gut microbiota
Ruminococcaceae
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453021000537
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