Repression of ZNFX1 by LncRNA ZFAS1 mediates tobacco-induced pulmonary carcinogenesis

Repression of ZNFX1 by LncRNA ZFAS1 mediates tobacco-induced pulmonary carcinogenesis

Abstract Background Despite exhaustive research efforts, integrated genetic and epigenetic mechanisms contributing to tobacco-induced initiation and progression of lung cancers have yet to be fully elucidated. In particular, limited information is available regarding dysregulation of noncoding RNAs...

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Main Authors: Sichuan Xi, Jigui Shan, Xinwei Wu, Haitao Wang, Mary R. Zhang, Shakirat Oyetunji, Hong Xu, Zuoxiang Xiao, Tuana Tolunay, Shamus R. Carr, Chuong D. Hoang, David S. Schrump
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cellular & Molecular Biology Letters
Subjects:
Lung cancer
Epigenetics
Noncoding RNA
ZNFX1
ZFAS1
Cigarette smoke
Online Access:https://doi.org/10.1186/s11658-025-00705-x
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https://doi.org/10.1186/s11658-025-00705-x

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