Tumor‐associated macrophages: potential role in skeletal involvement in classic Hodgkin lymphoma

Tumor‐associated macrophages: potential role in skeletal involvement in classic Hodgkin lymphoma

Abstract The biology of tumor spread to bone is poorly understood, not least in classic Hodgkin lymphoma (cHL). We used gene expression profiling and immunohistochemistry to characterize the nodal tumor microenvironment of cHL cases with and without skeletal involvement at diagnosis. Gene expression...

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Main Authors: Maja Dam Andersen, Katharina Wolter, Marie Hairing Enemark, Mette Abildgaard Pedersen, Lars Christian Gormsen, Kristina Lystlund Lauridsen, Jørn Starklint, Stephen Jacques Hamilton‐Dutoit, Francesco d'Amore, Maja Ludvigsen, Peter Kamper
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:The Journal of Pathology: Clinical Research
Subjects:
classic Hodgkin lymphoma (cHL)
bone
microenvironment
gene expression
CD68
CD163
Online Access:https://doi.org/10.1002/2056-4538.70038
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