SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic–smoking interaction analysis

SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic–smoking interaction analysis

Smoking cessation prolongs survival and decreases mortality of patients with non‐small‐cell lung cancer (NSCLC). In addition, epigenetic alterations of some genes are associated with survival. However, potential interactions between smoking cessation and epigenetics have not been assessed. Here, we...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruyang Zhang, Linjing Lai, Xuesi Dong, Jieyu He, Dongfang You, Chao Chen, Lijuan Lin, Ying Zhu, Hui Huang, Sipeng Shen, Liangmin Wei, Xin Chen, Yichen Guo, Liya Liu, Li Su, Andrea Shafer, Sebastian Moran, Thomas Fleischer, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, Yongyue Wei, Feng Chen, David C. Christiani
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Molecular Oncology
Subjects:
DNA methylation
interaction analysis
molecular cancer epidemiology
non‐small‐cell lung cancer
overall survival
smoking cessation
Online Access:https://doi.org/10.1002/1878-0261.12482
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1002/1878-0261.12482

Similar Items