Nerve repair with polylactic acid and inosine treatment enhance regeneration and improve functional recovery after sciatic nerve transection

Nerve repair with polylactic acid and inosine treatment enhance regeneration and improve functional recovery after sciatic nerve transection

BackgroundFollowing transection, nerve repair using the polylactic acid (PLA) conduit is an effective option. In addition, inosine treatment has shown potential to promote nerve regeneration. Therefore, this study aimed to investigate the regenerative potential of inosine after nerve transection and...

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Main Authors: Fellipe Soares dos Santos Cardoso, Guilherme dos Santos Maria, Fernanda Marques Pestana, Ricardo Cardoso, Bruna dos Santos Ramalho, Luiza dos Santos Heringer, Tiago Bastos Taboada, Ana Maria Blanco Martinez, Fernanda Martins de Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
nerve repair
inosine
sciatic nerve transection
nerve regeneration
A2A receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1525024/full
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https://www.frontiersin.org/articles/10.3389/fncel.2024.1525024/full

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