Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review

<b>Background:</b> The new frontiers of computer-based surgery, technology, and material advances, have allowed for customized 3D printed manufacturing to become widespread in guided bone regeneration (GBR) in oral implantology. The shape, structural, mechanical, and biological manufactu...

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Main Authors: Federica Di Spirito, Francesco Giordano, Maria Pia Di Palo, Cosimo Ferraro, Luigi Cecere, Eugenio Frucci, Mario Caggiano, Roberto Lo Giudice
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Dentistry Journal
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Online Access:https://www.mdpi.com/2304-6767/12/10/303
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author Federica Di Spirito
Francesco Giordano
Maria Pia Di Palo
Cosimo Ferraro
Luigi Cecere
Eugenio Frucci
Mario Caggiano
Roberto Lo Giudice
author_facet Federica Di Spirito
Francesco Giordano
Maria Pia Di Palo
Cosimo Ferraro
Luigi Cecere
Eugenio Frucci
Mario Caggiano
Roberto Lo Giudice
author_sort Federica Di Spirito
collection DOAJ
description <b>Background:</b> The new frontiers of computer-based surgery, technology, and material advances, have allowed for customized 3D printed manufacturing to become widespread in guided bone regeneration (GBR) in oral implantology. The shape, structural, mechanical, and biological manufacturing characteristics achieved through 3D printing technologies allow for the customization of implant-prosthetic rehabilitations and GBR procedures according to patient-specific needs, reducing complications and surgery time. Therefore, the present narrative review aims to elucidate the 3D-printing digital radiographic process, materials, indications, 3D printed manufacturing-controlled characteristics, histological findings, complications, patient-reported outcomes, and short- and long-term clinical considerations of customized 3D printed mesh, membranes, bone substitutes, and dental implants applied to GBR in oral implantology. <b>Methods:</b> An electronic search was performed through MEDLINE/PubMed, Scopus, BioMed Central, and Web of Science until 30 June 2024. <b>Results:</b> Three-dimensionally printed titanium meshes and bone substitutes registered successful outcomes in vertical/horizontal bone defect regeneration. Three-dimensionally printed polymeric membranes could link the advantages of conventional resorbable and non-resorbable membranes. Few data on customized 3D printed dental implants and abutments are available, but in vitro and animal studies have shown new promising designs that could improve their mechanical properties and tribocorrosion-associated complications. <b>Conclusions:</b> While 3D printing technology has demonstrated potential in GBR, additional human studies are needed to evaluate the short- and long-term follow-up of peri-implant bone levels and volumes following prosthetic functional loading.
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spelling doaj-art-623c55bd915440eb9cb15cc2bb9c1b4e2025-08-20T02:10:59ZengMDPI AGDentistry Journal2304-67672024-09-01121030310.3390/dj12100303Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative ReviewFederica Di Spirito0Francesco Giordano1Maria Pia Di Palo2Cosimo Ferraro3Luigi Cecere4Eugenio Frucci5Mario Caggiano6Roberto Lo Giudice7Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, SA, ItalyDepartment of Human Pathology in Adulthood and Childhood “G. Barresi”, University Hospital “G. Martino” of Messina, Via Consolare Valeria 1, 98123 Messina, ME, Italy<b>Background:</b> The new frontiers of computer-based surgery, technology, and material advances, have allowed for customized 3D printed manufacturing to become widespread in guided bone regeneration (GBR) in oral implantology. The shape, structural, mechanical, and biological manufacturing characteristics achieved through 3D printing technologies allow for the customization of implant-prosthetic rehabilitations and GBR procedures according to patient-specific needs, reducing complications and surgery time. Therefore, the present narrative review aims to elucidate the 3D-printing digital radiographic process, materials, indications, 3D printed manufacturing-controlled characteristics, histological findings, complications, patient-reported outcomes, and short- and long-term clinical considerations of customized 3D printed mesh, membranes, bone substitutes, and dental implants applied to GBR in oral implantology. <b>Methods:</b> An electronic search was performed through MEDLINE/PubMed, Scopus, BioMed Central, and Web of Science until 30 June 2024. <b>Results:</b> Three-dimensionally printed titanium meshes and bone substitutes registered successful outcomes in vertical/horizontal bone defect regeneration. Three-dimensionally printed polymeric membranes could link the advantages of conventional resorbable and non-resorbable membranes. Few data on customized 3D printed dental implants and abutments are available, but in vitro and animal studies have shown new promising designs that could improve their mechanical properties and tribocorrosion-associated complications. <b>Conclusions:</b> While 3D printing technology has demonstrated potential in GBR, additional human studies are needed to evaluate the short- and long-term follow-up of peri-implant bone levels and volumes following prosthetic functional loading.https://www.mdpi.com/2304-6767/12/10/3033D printingguided bone regenerationGBRoralmeshmembrane
spellingShingle Federica Di Spirito
Francesco Giordano
Maria Pia Di Palo
Cosimo Ferraro
Luigi Cecere
Eugenio Frucci
Mario Caggiano
Roberto Lo Giudice
Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
Dentistry Journal
3D printing
guided bone regeneration
GBR
oral
mesh
membrane
title Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
title_full Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
title_fullStr Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
title_full_unstemmed Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
title_short Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review
title_sort customized 3d printed mesh membrane bone substitute and dental implant applied to guided bone regeneration in oral implantology a narrative review
topic 3D printing
guided bone regeneration
GBR
oral
mesh
membrane
url https://www.mdpi.com/2304-6767/12/10/303
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