NanoBinder: a machine learning assisted nanobody binding prediction tool using Rosetta energy scores

Abstract Nanobodies offer significant therapeutic potential due to their small size, stability, and versatility. Although advancements in computational protein design have made designing de novo nanobodies increasingly feasible, there are limited tools specifically tailored for this purpose. Rosetta...

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Bibliographic Details
Main Authors: Palistha Shrestha, Chandana S. Talwar, Jeevan Kandel, Kwang-Hyun Park, Kil To Chong, Eui-Jeon Woo, Hilal Tayara
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Cheminformatics
Online Access:https://doi.org/10.1186/s13321-025-01040-1
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