A comparison of genomic methods to assess DNA replication timing

A comparison of genomic methods to assess DNA replication timing

Abstract Replication timing (RT), the temporal order in which genomic regions replicate, is considered a functional feature of multiple cellular processes and chromatin organization. Two approaches to measure RT are the Repli-seq and DNA copy number (also called S/G1) methods. We previously adapted...

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Bibliographic Details
Main Authors: Emily Wheeler, Leigh Mickelson-Young, Emily E. Wear, Mason Burroughs, Hank W. Bass, Lorenzo Concia, William F. Thompson, Linda Hanley-Bowdoin
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-02699-0
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