Decoding and reprogramming of the biosynthetic networks of mushroom-derived bioactive type II ganoderic acids in yeast

Abstract Mushroom’s specialized secondary metabolites possess important pharmacological activities, but their biosynthetic pathway elucidation is extremely challenging, not to mention reprogramming of their biosynthetic networks to target metabolites. By taking Ganoderma lucidum, a famous traditiona...

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Bibliographic Details
Main Authors: Qin Wang, Ye Li, Shunhan Zhang, Wei Yuan, Zeqian Du, Ting Shi, Zhao Chang, Xingye Zhai, Yinhua Lu, Meng Wang, Juan Guo, Jian-Jiang Zhong, Han Xiao
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-025-00812-1
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