Evolution of tumor stress response during cytoreductive surgery for ovarian cancer

Evolution of tumor stress response during cytoreductive surgery for ovarian cancer

Summary: Upfront treatment for patients with advanced high-grade serous ovarian cancer (HGSOC) includes a multi-hour cytoreductive surgery. Although the procedure is necessary for maximal tumor cytoreduction, understanding of the biology of systemic and intratumoral responses induced by surgical cyt...

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Main Authors: Aaron M. Praiss, Lea A. Moukarzel, Yingjie Zhu, Ana Leda F. Longhini, Fatemeh Derakhshan, Timothy Hoang, Giulio Pesci, Hunter Green, Melih A. Ozsoy, Etta Hanlon, Ryan Kahn, Melica Nourmoussavi Brodeur, Tiffany Sia, Nadeem R. Abu-Rustum, Ginger Gardner, Kara Long Roche, Yukio Sonoda, Oliver Zivanovic, Dennis S. Chi, Taha Merghoub, Rui Gardner, Britta Weigelt, Dmitriy Zamarin
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225005784
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http://www.sciencedirect.com/science/article/pii/S2589004225005784

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