Rat Models in Post-Traumatic Stress Disorder Research: Strengths, Limitations, and Implications for Translational Studies

Rat Models in Post-Traumatic Stress Disorder Research: Strengths, Limitations, and Implications for Translational Studies

Post-Traumatic Stress Disorder (PTSD) is a multifaceted psychiatric disorder triggered by traumatic events, leading to prolonged psychological distress and varied symptoms. Rat models have been extensively used to explore the biological, behavioral, and neurochemical underpinnings of PTSD. This revi...

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Bibliographic Details
Main Authors: Alexey Sarapultsev, Maria Komelkova, Oleg Lookin, Sergey Khatsko, Evgenii Gusev, Alexander Trofimov, Tursonjan Tokay, Desheng Hu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pathophysiology
Subjects:
ethological validity
model limitations
neuroendocrine factors
pharmacological interventions
PTSD
rats
Online Access:https://www.mdpi.com/1873-149X/31/4/51
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