A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has proven effective in treating the major motor symptoms of advanced Parkinson's disease (PD). The aim of this study was to learn which laryngeal and articulatory acoustic features changed in patients who were reported to have worse...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.4061/2011/796205 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560385952055296 |
|---|---|
| author | Christopher Dromey Suzy Bjarnason |
| author_facet | Christopher Dromey Suzy Bjarnason |
| author_sort | Christopher Dromey |
| collection | DOAJ |
| description | Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has proven effective in treating the major motor symptoms of advanced Parkinson's disease (PD). The aim of this study was to learn which laryngeal and articulatory acoustic features changed in patients who were reported to have worse speech with stimulation. Six volunteers with PD who had bilateral STN electrodes were recorded with DBS turned on or off. Perceptual ratings reflected poorer speech performance with DBS on. Acoustic measures of articulation (corner vowel formants, diphthong slopes, and a spirantization index) and phonation (perturbation, long-term average spectrum) as well as verbal fluency scores showed mixed results with DBS. Some speakers improved while others became worse on individual measures. The magnitude of DBS effects was not predictable based on the patients' demographic characteristics. Future research involving adjustments to stimulator settings or electrode placement may be beneficial in limiting the negative effects of DBS on speech. |
| format | Article |
| id | doaj-art-618f4af1b7f147879793e7e4af57c04f |
| institution | Kabale University |
| issn | 2042-0080 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-618f4af1b7f147879793e7e4af57c04f2025-02-03T01:27:40ZengWileyParkinson's Disease2042-00802011-01-01201110.4061/2011/796205796205A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's DiseaseChristopher Dromey0Suzy Bjarnason1Department of Communication Disorders, Brigham Young University, Provo, UT 84602, USADepartment of Communication Disorders, Brigham Young University, Provo, UT 84602, USADeep brain stimulation (DBS) of the subthalamic nucleus (STN) has proven effective in treating the major motor symptoms of advanced Parkinson's disease (PD). The aim of this study was to learn which laryngeal and articulatory acoustic features changed in patients who were reported to have worse speech with stimulation. Six volunteers with PD who had bilateral STN electrodes were recorded with DBS turned on or off. Perceptual ratings reflected poorer speech performance with DBS on. Acoustic measures of articulation (corner vowel formants, diphthong slopes, and a spirantization index) and phonation (perturbation, long-term average spectrum) as well as verbal fluency scores showed mixed results with DBS. Some speakers improved while others became worse on individual measures. The magnitude of DBS effects was not predictable based on the patients' demographic characteristics. Future research involving adjustments to stimulator settings or electrode placement may be beneficial in limiting the negative effects of DBS on speech.http://dx.doi.org/10.4061/2011/796205 |
| spellingShingle | Christopher Dromey Suzy Bjarnason A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease Parkinson's Disease |
| title | A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease |
| title_full | A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease |
| title_fullStr | A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease |
| title_full_unstemmed | A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease |
| title_short | A Preliminary Report on Disordered Speech with Deep Brain Stimulation in Individuals with Parkinson's Disease |
| title_sort | preliminary report on disordered speech with deep brain stimulation in individuals with parkinson s disease |
| url | http://dx.doi.org/10.4061/2011/796205 |
| work_keys_str_mv | AT christopherdromey apreliminaryreportondisorderedspeechwithdeepbrainstimulationinindividualswithparkinsonsdisease AT suzybjarnason apreliminaryreportondisorderedspeechwithdeepbrainstimulationinindividualswithparkinsonsdisease AT christopherdromey preliminaryreportondisorderedspeechwithdeepbrainstimulationinindividualswithparkinsonsdisease AT suzybjarnason preliminaryreportondisorderedspeechwithdeepbrainstimulationinindividualswithparkinsonsdisease |