Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis

Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis

BackgroundEmerging evidence underscores the comorbidity mechanisms among autoimmune diseases (AIDs), with innovative technologies such as single-cell RNA sequencing (scRNA-seq) significantly advancing the explorations in this field. This study aimed to investigate the shared genes among three AIDs—M...

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Bibliographic Details
Main Authors: Xiaofang Liu, Bin Li, Yuxi Lin, Xueying Ma, Yingying Liu, Lili Ma, Xiaomeng Ma, Xia Wang, Nanjing Li, Xiaoyun Liu, Xiaohong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
multiple sclerosis (MS)
systemic lupus erythematosus (SLE)
rheumatoid arthritis (RA)
WGCNA
bioinformatics
DEGs
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2024.1520050/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2024.1520050/full

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