An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration

An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration

Background. Diabetic retinopathy (DR) is a leading cause of blindness in working-age populations. Proper in vitro DR models are crucial for exploring pathophysiology and identifying novel therapeutic targets. This study establishes a rational in vitro diabetic retinal neuronal-endothelial dysfunctio...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qiyun Wang, Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Bingjie Qiu, Xiaosi Chen, Xiao Lin, Yao Nie
Format:	Article
Language:	English
Published:	Wiley 2021-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2021/9765119
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Vascular Inflammation and Endothelial Dysfunction in Experimental Hypertension
by: Carmine Savoia, et al.
Published: (2011-01-01)

Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy
by: Xinyuan Zhang, et al.
Published: (2021-01-01)

Targeting Endothelial Dysfunction in Vascular Complications Associated with Diabetes
by: Arpeeta Sharma, et al.
Published: (2012-01-01)

CCAAT/Enhancer-Binding Protein β Mediates Oxygen-Induced Retinal Neovascularization via Retinal Vascular Damage and Vascular Endothelial Growth Factor
by: Tingting Li, et al.
Published: (2020-01-01)

The Difference in Translaminar Pressure Gradient and Neuroretinal Rim Area in Glaucoma and Healthy Subjects
by: Lina Siaudvytyte, et al.
Published: (2014-01-01)

Endothelial Dysfunction and Diabetes: Effects on Angiogenesis, Vascular Remodeling, and Wound Healing
by: Gopi Krishna Kolluru, et al.
Published: (2012-01-01)

Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy
by: Fatma Al Zahraa Sherai, et al.
Published: (2025-02-01)

Comparison between Vascular Endothelial Growth Factor and Platelet-Derived Growth Factor Levels in Rhegmatogenous Retinal Detachment
by: Andi Muhammad Ichsan, et al.
Published: (2021-01-01)

Enhanced Visual Attentional Modulation in Patients with Inherited Peripheral Retinal Degeneration in the Absence of Cortical Degeneration
by: Sónia Ferreira, et al.
Published: (2019-01-01)

Endothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance dialysis
by: Dan-Dan Yao, et al.
Published: (2025-12-01)

Anti-vascular Endothelial Growth Factor Outpatient Treatment Patterns in Patients with Exudative Age-related Macular Degeneration from a Japanese Hospital Claims Database
by: Tomohiro Iida, et al.
Published: (2014-07-01)

Relationship of Retinal Vessel Caliber with Age-Related Macular Degeneration
by: Sara Toulouie, et al.
Published: (2022-01-01)

Inherited Retinal Degeneration: Genetics, Disease Characterization, and Outcome Measures
by: Naheed W. Khan, et al.
Published: (2017-01-01)

Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells
by: Lidan Xue, et al.
Published: (2023-01-01)

The Beneficial Role of Nrf2 in the Endothelial Dysfunction of Atherosclerosis
by: Zixia Huang, et al.
Published: (2022-01-01)

Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells
by: Yunfei Chai, et al.
Published: (2020-01-01)

The Effects of Previous Amenorrhea on Endothelial and Vascular Function
by: Katherine T. Williford, et al.
Published: (2025-01-01)

Endothelial Progenitors as Tools to Study Vascular Disease
by: Reinhold J. Medina, et al.
Published: (2012-01-01)

Outer retina micro-inflammation is driven by T cell responses prior to retinal degeneration in early age-related macular degeneration
by: Lucas Stürzbecher, et al.
Published: (2025-02-01)

Anti-Vascular Endothelial Growth Factor Agents for Ocular Angiogenesis and Vascular Permeability
by: Toshiaki Kubota, et al.
Published: (2012-01-01)

Retinal vascular geometry and its association to silent brain infarction
by: Jing Wang, et al.
Published: (2025-01-01)

UFMylation maintains YAP stability to promote vascular endothelial cell senescence
by: Yanan Liu, et al.
Published: (2025-02-01)

Arginase Inhibitor in the Pharmacological Correction of Endothelial Dysfunction
by: Mihail V. Pokrovskiy, et al.
Published: (2011-01-01)

Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy
by: Jianbo He, et al.
Published: (2015-01-01)

Antivascular Endothelial Growth Factor Agents for Neovascular Age-Related Macular Degeneration
by: Ilias Zampros, et al.
Published: (2012-01-01)

Combined Transplantation of Adipose Tissue-Derived Stem Cells and Endothelial Progenitor Cells Improve Diabetic Erectile Dysfunction in a Rat Model
by: Qiyun Yang, et al.
Published: (2020-01-01)

Glycoconjugates and Related Molecules in Human Vascular Endothelial Cells
by: Norihiko Sasaki, et al.
Published: (2013-01-01)

Cellular Signaling in Müller Glia: Progenitor Cells for Regenerative and Neuroprotective Responses in Pharmacological Models of Retinal Degeneration
by: Yang Liu, et al.
Published: (2019-01-01)

Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding
by: Meiting Shi, et al.
Published: (2025-01-01)

Effect of Lower Extremity Bypass Surgery on Inflammatory Reaction and Endothelial Dysfunction in Type 2 Diabetic Patients
by: Pei-Hsuan Tsai, et al.
Published: (2009-01-01)

Ibuprofen reduces inflammation, necroptosis and protects photoreceptors from light-induced retinal degeneration
by: Ping-Wu Zhang, et al.
Published: (2025-01-01)

EFFICIENT RETINAL IMAGE SEGMENTATION BY U-NET FOR AGE-RELATED MACULAR DEGENERATION DIAGNOSIS
by: S Sujatha, et al.
Published: (2024-12-01)

Posttraumatic Stress Disorder Is Associated With Endothelial Dysfunction in Women With HIV
by: Nishant Vatsa, MD, et al.
Published: (2025-02-01)

The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa
by: Francesco Saverio Sorrentino, et al.
Published: (2015-01-01)

Mural cell dysfunction contributes to diastolic heart failure by promoting endothelial dysfunction and vessel remodelling
by: Mandy O. J. Grootaert, et al.
Published: (2025-02-01)

Peripheral endothelial dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome
by: Nadja Scherbakov, et al.
Published: (2020-06-01)

Anderson–Fabry Disease: From Endothelial Dysfunction to Emerging Therapies
by: Cosimo A. Stamerra, et al.
Published: (2021-01-01)

Endothelial Dysfunction Correlates with Liver Fibrosis in Chronic HCV Infection
by: Michele Barone, et al.
Published: (2015-01-01)

15-Lipoxygenase-1 Is Involved in the Effects of Atorvastatin on Endothelial Dysfunction
by: Peng Zhang, et al.
Published: (2016-01-01)

Three Cases of Organized Hematoma of the Maxillary Sinus: Clinical Features and Immunohistological Studies for Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor 2 Expressions
by: Shoichiro Imayoshi, et al.
Published: (2015-01-01)