Unveiling the role of PPIF and macrophage subtypes in LSCC progression via single-cell and exosome RNA sequencing

Unveiling the role of PPIF and macrophage subtypes in LSCC progression via single-cell and exosome RNA sequencing

Abstract Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignancy with a rising incidence over time. The tumor microenvironment (TME) plays a crucial role in LSCC development, yet the precise cellular characteristics of laryngeal cancer and its TME remain unclear. Here, we employed...

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Bibliographic Details
Main Authors: Jianchao Wang, Chunhan Liu, Tailin Wu, Lei Tan, Jiangyan Wang, Wenliang Zhang, Yang Liu, Xudong Wei, Di Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
LSCC
Single-cell RNA
Exosomes
Macrophage
PPIF
Online Access:https://doi.org/10.1038/s41598-025-93584-3
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https://doi.org/10.1038/s41598-025-93584-3

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