Examination of common culture medium for human hepatocytes and engineered heart tissue: Towards an evaluation of cardiotoxicity associated with hepatic drug metabolism in vitro.

Cardiotoxicity associated with hepatic metabolism and drug-drug interactions is a serious concern. Predicting drug toxicity using animals remains challenging due to species and ethical concerns, necessitating the need to develop alternative approaches. Drug cardiotoxicity associated with hepatic met...

Full description

Saved in:
Bibliographic Details
Main Authors: Shinichiro Horiuchi, Nanae Koda, Yui Ikeda, Yuto Tanaka, Yusuke Masuo, Yukio Kato, Daiju Yamazaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0315997
Tags: Add Tag
No Tags, Be the first to tag this record!