First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma
Primary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumor with only a few isolated case reports in the medical literature. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or endoscopic ultrasound-guided core biopsy (EUS-CB) is a safe, effective modality for sampling l...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/8196051 |
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| author | Shaunak R. Mulani Patrick Stoner Alexander Schlachterman Hans K. Ghayee Li Lu Anand Gupte |
| author_facet | Shaunak R. Mulani Patrick Stoner Alexander Schlachterman Hans K. Ghayee Li Lu Anand Gupte |
| author_sort | Shaunak R. Mulani |
| collection | DOAJ |
| description | Primary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumor with only a few isolated case reports in the medical literature. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or endoscopic ultrasound-guided core biopsy (EUS-CB) is a safe, effective modality for sampling lesions in the gastrointestinal tract and adjacent organs, including the adrenal glands. We describe the case of a 50-year-old male presenting with abdominal pain and unintentional weight loss over the course of one year. CT imaging revealed an 8.1 cm heterogeneous left adrenal mass with PET-confirmed metastases to the liver and lung. Pheochromocytoma was ruled out. Adrenal cortical carcinoma was the other critical differential diagnosis. As the patient was not a candidate for surgery, an EUS-FNA and CB were performed on this left adrenal mass revealing a spindle cell neoplasm with extensive necrosis confirming the diagnosis of primary leiomyosarcoma. The patient was treated with chemotherapy with palliative radiation. This case demonstrates the utility of EUS-FNA or CB as modalities that can aid in the diagnosis of adrenal lesions in specific circumstances. |
| format | Article |
| id | doaj-art-611bd0cdad0a4a84b6bd0d11f711b930 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-611bd0cdad0a4a84b6bd0d11f711b9302025-02-03T01:07:02ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362018-01-01201810.1155/2018/81960518196051First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal LeiomyosarcomaShaunak R. Mulani0Patrick Stoner1Alexander Schlachterman2Hans K. Ghayee3Li Lu4Anand Gupte5Department of Internal Medicine, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USADepartment of Internal Medicine, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USADivision of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, PA, USADivision of Endocrinology, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USADivision of Pathology, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USADivision of Gastroenterology and Hepatology, University of Florida and Malcom Randall VA Medical Center, Gainesville, FL, USAPrimary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumor with only a few isolated case reports in the medical literature. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) or endoscopic ultrasound-guided core biopsy (EUS-CB) is a safe, effective modality for sampling lesions in the gastrointestinal tract and adjacent organs, including the adrenal glands. We describe the case of a 50-year-old male presenting with abdominal pain and unintentional weight loss over the course of one year. CT imaging revealed an 8.1 cm heterogeneous left adrenal mass with PET-confirmed metastases to the liver and lung. Pheochromocytoma was ruled out. Adrenal cortical carcinoma was the other critical differential diagnosis. As the patient was not a candidate for surgery, an EUS-FNA and CB were performed on this left adrenal mass revealing a spindle cell neoplasm with extensive necrosis confirming the diagnosis of primary leiomyosarcoma. The patient was treated with chemotherapy with palliative radiation. This case demonstrates the utility of EUS-FNA or CB as modalities that can aid in the diagnosis of adrenal lesions in specific circumstances.http://dx.doi.org/10.1155/2018/8196051 |
| spellingShingle | Shaunak R. Mulani Patrick Stoner Alexander Schlachterman Hans K. Ghayee Li Lu Anand Gupte First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma Case Reports in Gastrointestinal Medicine |
| title | First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma |
| title_full | First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma |
| title_fullStr | First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma |
| title_full_unstemmed | First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma |
| title_short | First Reported Case of Endoscopic Ultrasound-Guided Core Biopsy Yielding Diagnosis of Primary Adrenal Leiomyosarcoma |
| title_sort | first reported case of endoscopic ultrasound guided core biopsy yielding diagnosis of primary adrenal leiomyosarcoma |
| url | http://dx.doi.org/10.1155/2018/8196051 |
| work_keys_str_mv | AT shaunakrmulani firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma AT patrickstoner firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma AT alexanderschlachterman firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma AT hanskghayee firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma AT lilu firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma AT anandgupte firstreportedcaseofendoscopicultrasoundguidedcorebiopsyyieldingdiagnosisofprimaryadrenalleiomyosarcoma |