Cannabidiol Alleviates Chronic Prostatitis and Chronic Pelvic Pain Syndrome via CB2 Receptor Activation and TRPV1 Desensitization

Cannabidiol Alleviates Chronic Prostatitis and Chronic Pelvic Pain Syndrome via CB2 Receptor Activation and TRPV1 Desensitization

Purpose: This study elucidates the mechanism of the physiological effect of cannabidiol (CBD) by assessing its impact on lipopolysaccharide (LPS)-induced inflammation in RWPE-1 cells and prostatitis-induced by 17β-estradiol and dihydrotestosterone in a rat model, focusing on its therapeutic potent...

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Bibliographic Details
Main Authors: Jun Jie Piao, Soomin Kim, Dongho Shin, Hwa Jong Lee, Kyung-Hwa Jeon, Wen Jie Tian, Kyung Jae Hur, Jong Soo Kang, Hyun-Je Park, Joo Young Cha, Aeri Song, Sang-Hyuck Park, Mahadevan Rajasekaran, Woong Jin Bae, Sungjoo Kim Yoon, Sae Woong Kim
Format: Article
Language:English
Published: Korean Society for Sexual Medicine and Andrology 2025-01-01
Series:The World Journal of Men's Health
Subjects:
cannabidiol
prostatitis
receptor; cannabinoid; cb2
toll-like receptor 4
trpv1 receptor
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