Development of a rapid antigen-based lateral flow assay for tick-borne spotted fever rickettsioses.

Development of a rapid antigen-based lateral flow assay for tick-borne spotted fever rickettsioses.

Tick-borne spotted fever rickettsioses (SFRs) continue to cause severe illness and death in otherwise-healthy individuals due to lack of a timely and reliable diagnostic laboratory test. We recently identified a diagnostic biomarker for SFRs, the putative N-acetylmuramoyl-l-alanine amidase RC0497. H...

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Main Authors: Richard Willson, Yingxin Zhao, Kristen Brosamer, Yogita Pal, Lucas S Blanton, Esteban Arroyave, Carsen Roach, David H Walker, Katerina Kourentzi, Rong Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0312819
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https://doi.org/10.1371/journal.pone.0312819

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