Determination of the solubility of methyldopa in supercritical carbon dioxide for drug delivery applications: thermal analysis

Determination of the solubility of methyldopa in supercritical carbon dioxide for drug delivery applications: thermal analysis

Abstract The production of fine particles by green technology like supercritical carbon dioxide requires the assessment of substantial solubility data at high pressures. This study represents the first determination of the solubility of methyldopa in carbon dioxide at pressures and temperatures rang...

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Main Authors: Adil Farooq Wali, Sathvik Belagodu Sridhar, Sirajunisa Talath, Jayachithra Ramakrishna Pillai, Javedh Shareef, Mullaicharam Bhupathyraaj, B. K. Manjunatha Goud, Umme Hani
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Supercritical fluid
Solubility
Thermodynamic modeling
Semi-empirical and enthalpy
Online Access:https://doi.org/10.1038/s41598-024-84263-w
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