MiR-378 exaggerates angiogenesis and bone erosion in collagen-induced arthritis mice by regulating endoplasmic reticulum stress

MiR-378 exaggerates angiogenesis and bone erosion in collagen-induced arthritis mice by regulating endoplasmic reticulum stress

Abstract Rheumatoid arthritis (RA) is a chronic autoimmune disorder marked by pain, inflammation, and discomfort in the synovial joints. It is critical to understand the pathological mechanisms of RA progression. MicroRNA-378 (miR-378) is highly expressed in the synovium of RA patients and positivel...

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Main Authors: Zhengmeng Yang, Nan Hou, Wenxiang Cheng, Xuan Lu, Ming Wang, Shanshan Bai, Yuejun Lin, Yaofeng Wang, Sien Lin, Peng Zhang, Micky D. Tortorella, Lu Feng, Gang Li
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07193-5
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