Evaluation of low cryptococcal antigen titer as determined by the lateral flow assay in serum and cerebrospinal fluid among HIV-negative patients: a retrospective diagnostic accuracy study

Evaluation of low cryptococcal antigen titer as determined by the lateral flow assay in serum and cerebrospinal fluid among HIV-negative patients: a retrospective diagnostic accuracy study

Abstract Cryptococcosis is one of the most common opportunistic infections in both immunocompetent and immunocompromised hosts. Although the cryptococcal antigen (CrAg) lateral flow assay (LFA) has been widely used in clinical settings due to its high sensitivity and specificity, the diagnostic valu...

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Main Authors: Xuan Wang, Jia-Hui Cheng, Ling-Hong Zhou, Jun-Hao Zhu, Rui-Ying Wang, Hua-Zhen Zhao, Ying-Kui Jiang, Li-Ping Huang, Ching-Wan Yip, Chun-Xing Que, Min Zhu, Li-Ping Zhu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:IMA Fungus
Subjects:
Cryptococcosis
Meningitis
Low cryptococcal antigen titer
Lateral flow assay
Diagnostic accuracy
Online Access:http://link.springer.com/article/10.1186/s43008-020-00028-w
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http://link.springer.com/article/10.1186/s43008-020-00028-w

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