Single‐cell transcriptomic analysis of glioblastoma reveals pericytes contributing to the blood–brain–tumor barrier and tumor progression

Single‐cell transcriptomic analysis of glioblastoma reveals pericytes contributing to the blood–brain–tumor barrier and tumor progression

Abstract The blood–brain barrier is often altered in glioblastoma (GBM) creating a blood–brain–tumor barrier (BBTB) composed of pericytes. The BBTB affects chemotherapy efficacy. However, the expression signatures of BBTB‐associated pericytes remain unclear. We aimed to identify BBTB‐associated peri...

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Bibliographic Details
Main Authors: Yuzhe Li, Changwu Wu, Xinmiao Long, Xiangyu Wang, Wei Gao, Kun Deng, Bo Xie, Sen Zhang, Minghua Wu, Qing Liu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:MedComm
Subjects:
blood–brain–tumor barrier
glioblastoma
pericyte
prognosis
Online Access:https://doi.org/10.1002/mco2.70014
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https://doi.org/10.1002/mco2.70014

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