Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

The cystine/glutamate antiporter, solute carrier family 7 member 11 (SLC7A11), plays a crucial role in regulating redox homeostasis and cell death processes such as apoptosis and ferroptosis. These processes are implicated in various diseases, including cancer, organ injuries and neurodegenerative d...

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Main Authors: Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:FEBS Open Bio
Subjects:
acrylamide gel concentration
gel mobility
hydrophobicity
SDS‐PAGE
SLC7A11
transmembrane domain
Online Access:https://doi.org/10.1002/2211-5463.70019
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https://doi.org/10.1002/2211-5463.70019

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