Pseudogenes in the carcinogenesis: epithelial-to-mesenchymal transition process and cancer initiating cells

Pseudogenes in the carcinogenesis: epithelial-to-mesenchymal transition process and cancer initiating cells

Initially, pseudogenes were considered to be “junk DNA”, and their biological role was unclear. However, some of the pseudogenes are engaged in the process of cancerogenesis and perform essential functions in competing for endogenous RNA (ceRNA) networks and competing for RNA binding proteins (RBPs)...

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Main Authors: Tomasz Kolenda, Piotr Chałaj, Aleksandra Cichowicz, Aleksandra Trojańska, Andrzej Bałoniak, Malwina Kwaśniewska, Magda Odrobińska, Kacper Guglas, Joanna Kozłowska-Masłoń, Paulina Gieremek, Paulina Poter, Marlena Janiczek-Polewska, Anna Florczak-Substyk, Anna Przybyła, Patrycja Mantaj, Katarzyna Regulska, Beata Jadwiga Stanisz, Zefiryn Cybulski, Urszula Kazimierczak
Format: Article
Language:English
Published: Via Medica 2025-01-01
Series:Reports of Practical Oncology and Radiotherapy
Subjects:
non-coding RNA
pseudogene
cancer
epithelial-to-mesenchymal transition
cancer-initiating cells
EMT
CIC
biomarker
Online Access:https://journals.viamedica.pl/rpor/article/view/106096
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