Very low prevalence of Plasmodium falciparum histidine-rich protein 2 (pfhrp2) gene deletion in the Brazil, Venezuela, and Guyana tri-border

Very low prevalence of Plasmodium falciparum histidine-rich protein 2 (pfhrp2) gene deletion in the Brazil, Venezuela, and Guyana tri-border

Abstract Rapid Diagnostic Tests (RDTs) have been an important diagnostic tool for detecting P. falciparum malaria in resource-limited settings. Most tests are designed to detect the Histidine-rich Protein 2 (HRP2). Parasites lacking pfhrp2 and its homologous pfhrp3 have been reported in several regi...

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Main Authors: Maria Eduarda Pereira Mascarenhas, Jaime Louzada, Renato Amorim Rosa, Gabriela Maíra Pereira de Assis, Flora Satiko Kano, Joseli Oliveira-Ferreira, Tais Nobrega de Sousa
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Malaria
Plasmodium falciparum
pfhrp2
pfhrp3
RDT
Genetic diversity
Online Access:https://doi.org/10.1038/s41598-024-83727-3
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https://doi.org/10.1038/s41598-024-83727-3

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