Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries.
The global rise in antimicrobial resistance (AMR) is claiming the lives of more than 1.2 million people each year. According to the World Health Organization (WHO) this global health crisis is particularly acute in Africa, largely due to fragile and underfunded health systems. Efforts to combat this...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLOS Global Public Health |
| Online Access: | https://doi.org/10.1371/journal.pgph.0003688 |
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| author | Jacob Albin Korem Alhassan Clement Kamil Abdallah |
| author_facet | Jacob Albin Korem Alhassan Clement Kamil Abdallah |
| author_sort | Jacob Albin Korem Alhassan |
| collection | DOAJ |
| description | The global rise in antimicrobial resistance (AMR) is claiming the lives of more than 1.2 million people each year. According to the World Health Organization (WHO) this global health crisis is particularly acute in Africa, largely due to fragile and underfunded health systems. Efforts to combat this public health threat have led to the implementation of health system interventions worldwide aimed at managing and containing the spread of AMR. However, the literature on the real time impacts and the barriers that hinder the implementation of these interventions in the African context is limited. The objective of this scoping review was to identify AMR interventions in African health systems, their impact, and the challenges of the implementation. Drawing on Muka and colleague's 24 step approach for scoping reviews, two major public health databases (PubMed and Global Health) were searched for articles in accordance with the PRISMA guidelines resulting in 4,783 records. Screening and retrieval of articles was done using Rayyan software based on specified inclusion criteria and 36 articles included in the final list. These articles were synthesized after extracting specific data on AMR interventions and their impact on African health systems. The review identified four broad impacts of AMR interventions including 1. Reduction in antibiotics use, 2. Increased adherence to guidelines and protocols, 3. Enhanced laboratory-based AMR surveillance, 4. Development of antimicrobial stewardship (AMS) Action Plans and Teams. However, challenges such as poor laboratory infrastructure, logistical challenges, poor financial commitment and inadequate education and training were identified as challenges impeding the successful implementation of AMR interventions in Africa. Our findings reveal a range of successful AMR interventions in African health systems although infrastructural and financial challenges remain. Better standardization and reporting of AMR diagnosis while leveraging the available information is needed to improve the optimization of treatment guidelines across Africa. |
| format | Article |
| id | doaj-art-5ff8fb15083b4ad79c36b17d4eeeb390 |
| institution | Kabale University |
| issn | 2767-3375 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLOS Global Public Health |
| spelling | doaj-art-5ff8fb15083b4ad79c36b17d4eeeb3902025-02-05T05:50:30ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752024-01-0149e000368810.1371/journal.pgph.0003688Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries.Jacob Albin Korem AlhassanClement Kamil AbdallahThe global rise in antimicrobial resistance (AMR) is claiming the lives of more than 1.2 million people each year. According to the World Health Organization (WHO) this global health crisis is particularly acute in Africa, largely due to fragile and underfunded health systems. Efforts to combat this public health threat have led to the implementation of health system interventions worldwide aimed at managing and containing the spread of AMR. However, the literature on the real time impacts and the barriers that hinder the implementation of these interventions in the African context is limited. The objective of this scoping review was to identify AMR interventions in African health systems, their impact, and the challenges of the implementation. Drawing on Muka and colleague's 24 step approach for scoping reviews, two major public health databases (PubMed and Global Health) were searched for articles in accordance with the PRISMA guidelines resulting in 4,783 records. Screening and retrieval of articles was done using Rayyan software based on specified inclusion criteria and 36 articles included in the final list. These articles were synthesized after extracting specific data on AMR interventions and their impact on African health systems. The review identified four broad impacts of AMR interventions including 1. Reduction in antibiotics use, 2. Increased adherence to guidelines and protocols, 3. Enhanced laboratory-based AMR surveillance, 4. Development of antimicrobial stewardship (AMS) Action Plans and Teams. However, challenges such as poor laboratory infrastructure, logistical challenges, poor financial commitment and inadequate education and training were identified as challenges impeding the successful implementation of AMR interventions in Africa. Our findings reveal a range of successful AMR interventions in African health systems although infrastructural and financial challenges remain. Better standardization and reporting of AMR diagnosis while leveraging the available information is needed to improve the optimization of treatment guidelines across Africa.https://doi.org/10.1371/journal.pgph.0003688 |
| spellingShingle | Jacob Albin Korem Alhassan Clement Kamil Abdallah Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. PLOS Global Public Health |
| title | Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. |
| title_full | Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. |
| title_fullStr | Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. |
| title_full_unstemmed | Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. |
| title_short | Health system interventions and responses to anti-microbial resistance: A scoping review of evidence from 15 African countries. |
| title_sort | health system interventions and responses to anti microbial resistance a scoping review of evidence from 15 african countries |
| url | https://doi.org/10.1371/journal.pgph.0003688 |
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