Impact of Genetic Variants on Pregabalin Pharmacokinetics and Safety

Impact of Genetic Variants on Pregabalin Pharmacokinetics and Safety

<b>Background/Objectives:</b> Pregabalin is a useful therapeutic option for patients with anxiety or neuropathic pain. Genetic variants in certain genes encoding for transporters related to absorption and distribution could have an impact on the efficacy and safety of the drug. Furthermo...

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Main Authors: Sofía Calleja, Andrea Rodríguez-López, Dolores Ochoa, Sergio Luquero, Marcos Navares-Gómez, Manuel Román, Gina Mejia-Abril, Samuel Martín-Vilchez, Francisco Abad-Santos, Pablo Zubiaur
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceuticals
Subjects:
pregabalin
pharmacokinetics
safety
pharmacogenetics
Online Access:https://www.mdpi.com/1424-8247/18/2/151
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