Polygenic signals of sex differences in selection in humans from the UK Biobank.

Sex differences in the fitness effects of genetic variants can influence the rate of adaptation and the maintenance of genetic variation. For example, "sexually antagonistic" (SA) variants, which are beneficial for one sex and harmful for the other, can both constrain adaptation and increa...

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Bibliographic Details
Main Authors: Filip Ruzicka, Luke Holman, Tim Connallon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001768&type=printable
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