Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation
The accumulation of amyloid β-proteins (Aβ) in the extracellular space, forming insoluble plaques, is a primary pathological process underlying Alzheimer's disease (AD). Among the various Aβ species that appear during Aβ aggregation, Aβ oligomers are considered the most neurotoxic form. However...
Saved in:
Main Authors: | Hiroto Nakano, Sadao Hikishima, Makoto Mori, Jota Minamikawa, Daiki Muramatsu, Yasuhiro Sakashita, Tokuhei Ikeda, Moeko Noguchi-Shinohara, David B. Teplow, Kenjiro Ono |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
|
Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996124003772 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tau oligomers impair memory and synaptic plasticity through the cellular prion protein
by: Claudia Balducci, et al.
Published: (2025-01-01) -
Elucidation of delignification promotion mechanism by soda cooking with addition of anthraquinone derivative using phenolic β-O-4-type lignin model oligomer
by: Ke Luo, et al.
Published: (2025-01-01) -
C/EBPβ in Alzheimer’s disease: An integrative regulator of pathological mechanisms
by: Xiaoting Luo, et al.
Published: (2025-02-01) -
Targeting Soluble Amyloid Oligomers in Alzheimer’s Disease: A Hypothetical Model Study Comparing Intrathecal Pseudodelivery of mAbs Against Intravenous Administration
by: Manuel Menendez-Gonzalez
Published: (2025-01-01) -
Fourier Transform Infrared Spectroscopy Analysis as a Tool to Address Aβ Impact on Extracellular Vesicles
by: Margarida Vaz, et al.
Published: (2025-01-01)