Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach

Decoding the m6A epitranscriptomic landscape for biotechnological applications using a direct RNA sequencing approach

Abstract Epitranscriptomic modifications, particularly N6-methyladenosine (m6A), are crucial regulators of gene expression, influencing processes such as RNA stability, splicing, and translation. Traditional computational methods for detecting m6A from Nanopore direct RNA sequencing (DRS) data are c...

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Main Authors: Chuwei Liu, Heng Liang, Arabella H. Wan, Min Xiao, Lei Sun, Yiling Yu, Shijia Yan, Yuan Deng, Ruonian Liu, Juan Fang, Zhi Wang, Weiling He, Guohui Wan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56173-6
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https://doi.org/10.1038/s41467-025-56173-6

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