Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice

Combined dietary omega-3 and omega-6 fatty acids protect against hyperglycemia-associated retinopathy in neonatal mice

Retinopathy of prematurity (ROP) with early vessel loss (Phase I) followed by uncontrolled vessel growth (Phase II) causes visual impairment in premature infants. Although supplementation with omega-3 (n-3) docosahexaenoic acid (DHA) alone shows mixed results in preventing ROP, supplementation with...

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Main Authors: Myriam Boeck, Hitomi Yagi, Pia Lundgren, Aldina Pivodic, Anders K. Nilsson, Yan Zeng, Chuck T. Chen, Taku Kasai, Deokho Lee, Shen Nian, Victoria Hirst, Katherine Neilsen, Chaomei Wang, Jeff Lee, Mathew Yu, Andrew McCutcheon, Sasha A. Singh, Masanori Aikawa, Richard P. Bazinet, Zhongjie Fu, Ann Hellström, Lois EH Smith
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Pharmacological Research
Subjects:
Postnatal hyperglycemia
Retinopathy of prematurity
DHA
ARA
Retinal vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825003020
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