Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury

Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury

Traumatic brain injury (TBI) is a major cause of morbidity and mortality, not least in the elderly. The incidence of aged TBI patients has increased dramatically during the last decades. High age is a highly negative prognostic factor in TBI, and pharmacological treatment options are lacking. We use...

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Bibliographic Details
Main Authors: Georgios Michalettos, Fredrik Clausen, Elham Rostami, Niklas Marklund
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Neurotherapeutics
Subjects:
Traumatic brain injury
High age
7,8-DHF
White matter
Oligodendroglia
Axonal injury
Online Access:http://www.sciencedirect.com/science/article/pii/S1878747924001594
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http://www.sciencedirect.com/science/article/pii/S1878747924001594

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