Immunosenescence-related T cell phenotypes, structural brain imaging, and cognitive impairment in patients with schizophrenia: a moderated mediation analysis

Abstract Cognitive impairment is a core characteristic of schizophrenia. Immunosenescence has been consistently implicated in the cognitive dysfunction observed in neurodegenerative diseases, but how it may relate to cognitive deficits in schizophrenia is still unclear. We explored the associations...

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Main Authors: Na Li, Yanli Li, Ting Yu, Wenjin Chen, Mengzhuang Gou, Wenkai Zheng, Zhaofan Liu, Xiaoying Wang, Jiao Fang, Jinghui Tong, Song Chen, Baopeng Tian, Chiang-Shan R. Li, Li Tian, Yunlong Tan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-025-00650-w
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