Hypoxia-ischemia and sexual dimorphism: modeling mitochondrial dysfunction using brain organoids
Abstract Hypoxic–ischemic encephalopathy (HIE) is a leading cause of neurodevelopmental morbidities in full-term infants. There is strong evidence of sexual differences in hypoxic-ischemic (HI) injury where male neonates are at higher risk as they are subject to more pronounced neurological deficits...
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| Main Authors: | Romane Gaston-Breton, Clémence Disdier, Henrik Hagberg, Aloïse Mabondzo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Cell & Bioscience |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13578-025-01402-0 |
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