Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens

Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens

Abstract Background Fatty liver hemorrhage syndrome (FLHS) has become one of the major factors leading to the death of laying hen in caged egg production. FLHS is commonly associated with lipid peroxidation, hepatocyte injury, decreased antioxidant capacity, and inflammation. However, there are limi...

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Main Authors: Daojie Li, Kun Meng, Guohua Liu, Zhiguo Wen, Yunsheng Han, Weiwei Liu, Xin Xu, Liye Song, Hongying Cai, Peilong Yang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Microbiome
Subjects:
Fatty liver hemorrhage syndrome
Lactiplantibacillus plantarum FRT4
Oxidative stress
Gut microbiota
FoxO/TLR-4/NF-κB signaling pathway
Online Access:https://doi.org/10.1186/s40168-025-02083-0
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https://doi.org/10.1186/s40168-025-02083-0

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