SMYD2 inhibitors have no effect in improving non-alcoholic steatohepatitis in mice

IntroductionNonalcoholic steatohepatitis (NASH), characterized by progressive liver injury, inflammation, and fibrosis, is a leading chronic liver disease worldwide. Pharmacotherapy for NASH is thus urgently needed. Through a strategy of in vivo lineage tracing, it was recently discovered that delet...

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Bibliographic Details
Main Authors: Lanzexin Yang, Shixuan Zhuo, Xinyu Zhu, Xinhui Zhang, Zinan Wang, Yan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1480453/full
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