Analysis and validation of serum biomarkers in brucellosis patients through proteomics and bioinformatics

Analysis and validation of serum biomarkers in brucellosis patients through proteomics and bioinformatics

IntroductionThis study aims to utilize proteomics, bioinformatics, and machine learning algorithms to identify diagnostic biomarkers in the serum of patients with acute and chronic brucellosisMethodsProteomic analysis was conducted on serum samples from patients with acute and chronic brucellosis, a...

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Bibliographic Details
Main Authors: Xiao Li, Bo Wang, Xiaocong Li, Juan He, Yue Shi, Rui Wang, Dongwei Li, Ding Haitao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
brucellosis
biomarkers
proteomics
bioinformatics
differential expression analysis
weighted gene co-expression network analysis (WGCNA)
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1446339/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1446339/full

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