Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma

Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma

The indoleamine 2,3-dioxygenase-(IDO-) mediated microenvironment plays an important role in tumor immune escape. However, the inhibitory effects of IDO on the CD8+ tumour-infiltrating lymphocytes (CD8+ TILs) in esophageal squamous cell carcinoma (ESCC) have not been clarified yet. Here, we found tha...

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Bibliographic Details
Main Authors:	Ge Zhang, Wan-Li Liu, Lin Zhang, Jun-Ye Wang, Miao-Huan Kuang, Peng Liu, Yue-Hao Lin, Shu-Qin Dai, Jun Du
Format:	Article
Language:	English
Published:	Wiley 2011-01-01
Series:	Clinical and Developmental Immunology
Online Access:	http://dx.doi.org/10.1155/2011/384726
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