Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients

Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients

Abstract Background Wnt/β-catenin pathway has an important role in hepatocarcinogenesis. It has been involved in progression, growth, epithelial mesenchymal transition and metastasis of hepatocellular carcinoma (HCC). This pathway may represent a potential target for evolving treatment strategies. β...

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Bibliographic Details
Main Authors: Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Surgical and Experimental Pathology
Subjects:
β-catenin
Wnt2
CTNNB1
IHC
Gene mutation
Hepatocellular carcinoma
Online Access:https://doi.org/10.1186/s42047-025-00175-7
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https://doi.org/10.1186/s42047-025-00175-7

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