Anticancer potential of coumarins from the Ferulago genus
Cancer treatment needs better therapeutic agents with fewer side effects compared to the present anticancer and antitumor drugs. Possessing a wide range of chemicals, natural products are considered rich sources of bioactive compounds in treating a broad scope of diseases, especially cancer. Harness...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-01-01
|
| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625000165 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832583089720655872 |
|---|---|
| author | Mansour Mofasseri Elham Eini Saber Mofasseri Bahram Hanifehpour Fatemeh Zanbili Ahmad Poursattar Marjani |
| author_facet | Mansour Mofasseri Elham Eini Saber Mofasseri Bahram Hanifehpour Fatemeh Zanbili Ahmad Poursattar Marjani |
| author_sort | Mansour Mofasseri |
| collection | DOAJ |
| description | Cancer treatment needs better therapeutic agents with fewer side effects compared to the present anticancer and antitumor drugs. Possessing a wide range of chemicals, natural products are considered rich sources of bioactive compounds in treating a broad scope of diseases, especially cancer. Harness the power of coumarins, a natural compound that has shown remarkable efficacy in treating many cancers. This study was aimed to highlight the most promising coumarins from Ferulago genus, their mechanisms of action, and potential therapeutic applications in cancer treatment. In this regard, a broad literature study was conducted applying a considerable number of scientific databases, including Science Direct, Scopus, Web of Science, PubMed, Google Scholar, and EBSCO, to review the latest studies on the anticancer potential of Ferulago genus. The search was limited to studies published up to June 2024. In this review, a collection of diverse reports on Ferulago species with cytotoxic and anticancer activities, as well as isolated coumarins from this genus with anticancer potentials, are presented. The results showed that the Ferulago genus, an extensive reservoir of coumarins, is a promising source for discovering, improving, and designing groundbreaking anticancer and cytotoxic therapeutics. Accordingly, continued investigations into their pharmacological properties and therapeutic applications will be crucial in developing novel anticancer therapies, ultimately contributing to improved patient quality of life. |
| format | Article |
| id | doaj-art-5dfe4150cc954ad2bc0a84db1389097f |
| institution | Kabale University |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-5dfe4150cc954ad2bc0a84db1389097f2025-01-29T05:01:03ZengElsevierResults in Chemistry2211-71562025-01-0113102033Anticancer potential of coumarins from the Ferulago genusMansour Mofasseri0Elham Eini1Saber Mofasseri2Bahram Hanifehpour3Fatemeh Zanbili4Ahmad Poursattar Marjani5School of Chemistry, College of Science, University of Tehran, Tehran, IranDepartment of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, IranDepartment of Analytical Chemistry, Faculty of Chemistry, Urmia University, Urmia, IranDepartment of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, IranDepartment of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, IranDepartment of Organic Chemistry, Faculty of Chemistry, Urmia University, Urmia, Iran; Corresponding author.Cancer treatment needs better therapeutic agents with fewer side effects compared to the present anticancer and antitumor drugs. Possessing a wide range of chemicals, natural products are considered rich sources of bioactive compounds in treating a broad scope of diseases, especially cancer. Harness the power of coumarins, a natural compound that has shown remarkable efficacy in treating many cancers. This study was aimed to highlight the most promising coumarins from Ferulago genus, their mechanisms of action, and potential therapeutic applications in cancer treatment. In this regard, a broad literature study was conducted applying a considerable number of scientific databases, including Science Direct, Scopus, Web of Science, PubMed, Google Scholar, and EBSCO, to review the latest studies on the anticancer potential of Ferulago genus. The search was limited to studies published up to June 2024. In this review, a collection of diverse reports on Ferulago species with cytotoxic and anticancer activities, as well as isolated coumarins from this genus with anticancer potentials, are presented. The results showed that the Ferulago genus, an extensive reservoir of coumarins, is a promising source for discovering, improving, and designing groundbreaking anticancer and cytotoxic therapeutics. Accordingly, continued investigations into their pharmacological properties and therapeutic applications will be crucial in developing novel anticancer therapies, ultimately contributing to improved patient quality of life.http://www.sciencedirect.com/science/article/pii/S2211715625000165AnticancerCoumarinCytotoxicFerulagoNatural products |
| spellingShingle | Mansour Mofasseri Elham Eini Saber Mofasseri Bahram Hanifehpour Fatemeh Zanbili Ahmad Poursattar Marjani Anticancer potential of coumarins from the Ferulago genus Results in Chemistry Anticancer Coumarin Cytotoxic Ferulago Natural products |
| title | Anticancer potential of coumarins from the Ferulago genus |
| title_full | Anticancer potential of coumarins from the Ferulago genus |
| title_fullStr | Anticancer potential of coumarins from the Ferulago genus |
| title_full_unstemmed | Anticancer potential of coumarins from the Ferulago genus |
| title_short | Anticancer potential of coumarins from the Ferulago genus |
| title_sort | anticancer potential of coumarins from the ferulago genus |
| topic | Anticancer Coumarin Cytotoxic Ferulago Natural products |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625000165 |
| work_keys_str_mv | AT mansourmofasseri anticancerpotentialofcoumarinsfromtheferulagogenus AT elhameini anticancerpotentialofcoumarinsfromtheferulagogenus AT sabermofasseri anticancerpotentialofcoumarinsfromtheferulagogenus AT bahramhanifehpour anticancerpotentialofcoumarinsfromtheferulagogenus AT fatemehzanbili anticancerpotentialofcoumarinsfromtheferulagogenus AT ahmadpoursattarmarjani anticancerpotentialofcoumarinsfromtheferulagogenus |