Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany

Abstract Background Little is known about mortality from four disorder combinations: fully attributable to alcohol or tobacco, partly attributable to both alcohol and tobacco, to tobacco only, to alcohol only. Aim To analyze whether residents who had disclosed risky alcohol drinking or daily tobacco...

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Main Authors: Ulrich John, Hans-Jürgen Rumpf, Monika Hanke, Christian Meyer
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Substance Abuse Treatment, Prevention, and Policy
Subjects:
Online Access:https://doi.org/10.1186/s13011-025-00633-1
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author Ulrich John
Hans-Jürgen Rumpf
Monika Hanke
Christian Meyer
author_facet Ulrich John
Hans-Jürgen Rumpf
Monika Hanke
Christian Meyer
author_sort Ulrich John
collection DOAJ
description Abstract Background Little is known about mortality from four disorder combinations: fully attributable to alcohol or tobacco, partly attributable to both alcohol and tobacco, to tobacco only, to alcohol only. Aim To analyze whether residents who had disclosed risky alcohol drinking or daily tobacco smoking had a shorter time to death than non-risky drinkers and never daily smokers twenty years later according to the disorder combinations. Methods A random adult general population sample (4,075 study participants) of a northern German area had been interviewed in the years 1996–1997. Vital status and death certificate data were gathered 2017–2018. The data analysis included estimates of alcohol- or tobacco-attributable mortality using all conditions given in the death certificate and alternatively the underlying cause of death only. Results Among 573 deaths, 71.9–94.1% had any alcohol- or tobacco-attributable disorder depending on the estimate. Risky alcohol consumption and daily tobacco smoking at baseline were related to disorders in the death certificate according to the combinations. Deaths with an alcohol- and tobacco-attributable disorder were related to risky alcohol consumption (subhazard ratio 1.57; 95% confidence interval 1.25–1.98) and to daily tobacco smoking at baseline (subhazard ratio 1.85; 95% confidence interval 1.42–2.41). Conclusion First, more than 70% of the deceased persons had one or more alcohol- or tobacco-attributable disorders. This finding suggests that total mortality seems to be the suitable outcome if potential effects of alcohol or tobacco consumption in a general population are to be estimated. Second, the relations of risky alcohol consumption and tobacco smoking with time to death speak in favor of the validity of alcohol- and of tobacco-attributable disorders in death certificates and of considering both alcohol consumption and tobacco smoking if attributable deaths are to be estimated.
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spelling doaj-art-5ddda4bfc0a44053a9c7fad8156fd6a52025-01-26T12:15:34ZengBMCSubstance Abuse Treatment, Prevention, and Policy1747-597X2025-01-0120111110.1186/s13011-025-00633-1Estimating mortality attributable to alcohol or tobacco – a cohort study from GermanyUlrich John0Hans-Jürgen Rumpf1Monika Hanke2Christian Meyer3Dep Prevention Research and Social Medicine, University Medicine Greifswald, Institute of Community MedicineDepartment of Psychiatry and Psychotherapy, Research Group S:TEP, University of LübeckDep Prevention Research and Social Medicine, University Medicine Greifswald, Institute of Community MedicineDep Prevention Research and Social Medicine, University Medicine Greifswald, Institute of Community MedicineAbstract Background Little is known about mortality from four disorder combinations: fully attributable to alcohol or tobacco, partly attributable to both alcohol and tobacco, to tobacco only, to alcohol only. Aim To analyze whether residents who had disclosed risky alcohol drinking or daily tobacco smoking had a shorter time to death than non-risky drinkers and never daily smokers twenty years later according to the disorder combinations. Methods A random adult general population sample (4,075 study participants) of a northern German area had been interviewed in the years 1996–1997. Vital status and death certificate data were gathered 2017–2018. The data analysis included estimates of alcohol- or tobacco-attributable mortality using all conditions given in the death certificate and alternatively the underlying cause of death only. Results Among 573 deaths, 71.9–94.1% had any alcohol- or tobacco-attributable disorder depending on the estimate. Risky alcohol consumption and daily tobacco smoking at baseline were related to disorders in the death certificate according to the combinations. Deaths with an alcohol- and tobacco-attributable disorder were related to risky alcohol consumption (subhazard ratio 1.57; 95% confidence interval 1.25–1.98) and to daily tobacco smoking at baseline (subhazard ratio 1.85; 95% confidence interval 1.42–2.41). Conclusion First, more than 70% of the deceased persons had one or more alcohol- or tobacco-attributable disorders. This finding suggests that total mortality seems to be the suitable outcome if potential effects of alcohol or tobacco consumption in a general population are to be estimated. Second, the relations of risky alcohol consumption and tobacco smoking with time to death speak in favor of the validity of alcohol- and of tobacco-attributable disorders in death certificates and of considering both alcohol consumption and tobacco smoking if attributable deaths are to be estimated.https://doi.org/10.1186/s13011-025-00633-1Alcohol-attributable mortalityTobacco-attributable mortalityMortality cohort studyRisky alcohol consumptionTobacco smoking
spellingShingle Ulrich John
Hans-Jürgen Rumpf
Monika Hanke
Christian Meyer
Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
Substance Abuse Treatment, Prevention, and Policy
Alcohol-attributable mortality
Tobacco-attributable mortality
Mortality cohort study
Risky alcohol consumption
Tobacco smoking
title Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
title_full Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
title_fullStr Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
title_full_unstemmed Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
title_short Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany
title_sort estimating mortality attributable to alcohol or tobacco a cohort study from germany
topic Alcohol-attributable mortality
Tobacco-attributable mortality
Mortality cohort study
Risky alcohol consumption
Tobacco smoking
url https://doi.org/10.1186/s13011-025-00633-1
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