Nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable or recurrent pancreatic cancer: a multicenter observational study (NAPOLEON-2)

Nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable or recurrent pancreatic cancer: a multicenter observational study (NAPOLEON-2)

Background: Nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second- or later-line regimen after gemcitabine-based therapy for patients with unresectable or recurrent pancreatic cancer (urPC). However, limited prospective clinical data on the efficacy and safety of NFF...

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Main Authors: T. Shirakawa, M. Shimokawa, T. Otsuka, Y. Shinohara, K. Toyodome, W. Kusano, J. Nakazawa, T. Kodama, M. Kawahira, H. Shimokawa, T. Koike, F. Koga, S. Yunotani, S. Nakashita, N. Oza, S. Noge, K. Murayama, H. Oda, N. Mitsui, R. Kawasaki, T. Morikita, S. Takeshita, S. Arima, R. Shibata, A. Kakihara, T. Yoshihiro, T. Imajima, S. Yamaga, S. Arita, Y. Kawaguchi, K. Nishikawa, T. Inagaki, S. Otsu, H. Taguchi, K. Jikuya, T. Terada, T. Sakai, Y. Ueda, T. Sakae, H. Sawase, K. Nio, N. Araki, K. Sakai, Y. Ide, T. Shibuki, K. Miwa, Y. Kubotsu, A. Hosokawa, A. Komori, T. Honda, K. Tsuneyoshi, T. Fujita, T. Mizuta, K. Mitsugi
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:ESMO Gastrointestinal Oncology
Subjects:
nanoliposomal irinotecan
pancreatic cancer
chemotherapy
prospective
real-world data
Online Access:http://www.sciencedirect.com/science/article/pii/S2949819825000196
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