iVAE: an interpretable representation learning framework enhances clustering performance for single-cell data

Abstract Background Variational autoencoders (VAEs) serve as essential components in large generative models for extracting latent representations and have gained widespread application in biological domains. Developing VAEs specifically tailored to the unique characteristics of biological data is c...

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Bibliographic Details
Main Authors: Zeyu Fu, Chunlin Chen, Song Wang, Junping Wang, Shilei Chen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02315-7
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