Baseline abundance of Akkermansia muciniphila and Bacteroides acidifaciens in a healthy state predicts inflammation associated tumorigenesis in the AOM/DSS mouse model

Baseline abundance of Akkermansia muciniphila and Bacteroides acidifaciens in a healthy state predicts inflammation associated tumorigenesis in the AOM/DSS mouse model

Abstract Numerous studies demonstrate that intestinal microbiota contribute to colorectal cancer (CRC), which is often associated with dysbiosis. Most of the data were obtained from studies on CRC patients, making it challenging to determine whether alterations in microbiota are a consequence of the...

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Bibliographic Details
Main Authors: Kseniya M. Achasova, Olga A. Snytnikova, Kseniya E. Chanushkina, Maryana V. Morozova, Yuri P. Tsentalovich, Elena N. Kozhevnikova
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Gut microbiota
Colorectal cancer
Intestinal inflammation
Colitis-associated tumorigenesis
Akkermansia muciniphila
Bacteroides acidifaciens
Online Access:https://doi.org/10.1038/s41598-025-96514-5
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